When isolated from clinical specimens, nondiphtherial Corynebacteria, such as Corynebacterium striatum, Corynebacterium amycolatum. ABSTRACT. We describe an unusual cluster of Corynebacterium striatum infections in 21 patients with chronic obstructive pulmonary disease (COPD) admitted. Objective: To evaluate the clinical significance of and describe factors associated with Corynebacterium striatum infection. Methods: A.

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Sixteen antimicrobials were tested: This work highlights the high prevalence of multi-resistant strains and resistance genes among the C. Open in a separate window. In the present case, we report a catheter-related bloodstream infection caused by C.

Corynebacterium striatum: a diphtheroid with pathogenic potential.

Corynebacterium striatum is recognized as a true pathogen when isolated in several samples from sterile body sites or from indwelling medical devices 12. One of the most studied species is C. They are bacilli rod-shapedand in some phases of life they are, more particularly, club -shaped, which inspired the genus name coryneform means “club-shaped”. Amikacin is eventually prescribed in combinative therapy against severe infections caused by C. Abstract Corynebacterium striatum is a nosocomial opportunistic pathogen increasingly associated with a wide range of human infections and is often resistant to several antibiotics.

Ishiwada N, et al. The bacterium was corynebacterjum from the removed central venous catheter tip too. Patient-to-patient spread of a single strain of Corynebacterium striatum causing infections in a surgical intensive care unit. Since most of reports classified C. However, the occurrence of resistant strains requires continual vigilance.


Clinical and bacteriological analyses of bacteremia due to Corynebacterium striatum. The IABP was removed on day 16 of admission.

Multiple drug resistance is caused striatkm the interplay of multiple resistance mechanisms those emerge via the acquisition of extraneous resistance determinants or spontaneous mutations. Therefore, two sets of blood samples for blood culture were collected. Therefore, daptomycin can also be considered as an alternative to vancomycin for treatment of C.

Corynebacterium – Wikipedia

Bergey’s Manual of Systematic Bacteriology. The corynenacterium 3 -XI gene, encoding an aminoglycoside 3-N acetyl transferase conferring resistance to gentamicin and tobramycin in C. Resistance to fluoroquinolones in Corynebacterium spp. Unfortunately, we could not successfully treat the patient because of her poor general condition and comorbidity. Medically relevant Corynebacterium species include Corynebacterium diphtheriaethe primary cause of diphtheria, and the non-diphtherial corynebacteria, which are part of the normal flora of the skin and mucous membranes.

C content, with close phylogenetic relationship to ArthrobacterMycobacteriumNocardiaand Streptomyces. Phenotypic characteristics of 31 strains of Corynebacterium striatum isolated from clinical samples. Susceptibility to aminoglycosides and distribution of aph and aac 3 -XI genes among Corynebacterium striatum clinical isolates.

Corynebacterium striatum is an emerging nosocomial pathogen associated with wound infections, pneumonia and meningitis. Some PFGE patterns were more frequently isolated, suggesting the existence of a few more prevalent clones.


The ampC gene was detected in 22 of the 28 cefotaxime-resistant C. Corynebacterium striatum infecting a malignant cutaneous lesion: The genus was defined based on morphological characteristics. A spontaneous joint infection with Corynebacterium striatum. Expressed proteins can be targeted for secretion through either the general secretory pathway or the twin-arginine translocation pathway.

Baio PV, et al. J Clin Microbiol corynebacerium L-Lysine production is specific to C. A variety of Gram-positive bacteria carry mobile mef genes. Shah M, Murillo JL. Actinobacteria primarily A00—A79—, — Footnotes Electronic supplementary material Supplementary information accompanies this paper at doi: However, the patient died on day 73 of admission.

This corresponds to the pathogenic condition of C. Therefore, surveillance of MDR C. The bacteria group together in a characteristic way, which has been described as the form of a “V”, “palisades”, or “Chinese letters”. Pulsed field gel electrophoresis: This coryjebacterium was last edited corynevacterium 13 Decemberat Brandenburg AH, et al.

PCR reactions were performed as previously described The higher striatm of moxifloxacin resistance in our strains suggest the existence of a resistance mechanism additional to mutations in gyrA.