Shop online for a wide selection of Hemosure iFOB Test Kits: Collection Tubes For use with Hemosure iFOB Test Kits. Shop online for a wide selection of Hemosure iFOB Test Kits Qualitative, one- step, odorless iFOB test with high sensivity and specificity. Four products (Beckman/Coulter Hemoccult ICT, Hemosure iFOB test, Polymedco OC-Light IFOB, and Polymedco OC-Auto Micro 80) were.

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The WSLH representative said they purchase their samples from a vendor and do not have that information. The participants analyze the specimens and return the hemosute to the proficiency evaluator. A global conceptual model. In this manuscript, we have summarized the information on the fecal immunochemical tests analyzed across four proficiency testing programs. Comparison of immunochemical and guaiac-based fecal occult blood test in screening and surveillance for advanced colorectal neoplasms: Implications for clinical practice in hospital and outpatient settings.

Hemosure – Home of the one-step iFOB Test (FIT) for CRC Screening

BayMS, 2 and Barcey T. Comparison of guaiac-based and quantitative immunochemical fecal occult blood testing in a population at average risk undergoing colorectal cancer screening.

Clinical guidelines and rationale-update based on new evidence. Screening for colorectal cancer: However, some had low sensitivity and specificity and probably should not be used for population-based or other screening. Fourteen unique FIT brands were evaluated by at least one of the four proficiency testing programs. Validity of immunological faecal occult blood screening for colorectal cancer: National Center for Biotechnology InformationU.

If physicians and public health personnel are going to advocate for use of fecal immunochemical tests, then information on validity needs to be more readily available. As the recent cascade colorectal cancer screening guidelines are resource driven and emphasize doing what you can for screening with what you have, rather than choosing only one approach or not doing it at all, this additional perspective must be taken into consideration along with the viewpoint of the patient.


Author manuscript; available in PMC Jan 3. Individual laboratories are provided with unidentified specimens for testing. From this review of eight FITs, it appears that most tests do as they say they will do; i. Although there were a total of seven testing programs, some consider their information proprietary and would not share it with us.

After the review of the 75 product names, 34 were determined to be FITs. It is important for healthcare providers to be aware of the variation in the products available for CRC screening. It is nearly impossible to make an informed decision with the information currently available.

Hemosure DUO-IFOB – McKesson Medical-Surgical

Choice, usage and clinical applications. LevyPhD, MD 1, 2. As a healthcare worker selecting a product for fecal occult blood testing, this summary of results has provided information about a few FITs that generally produce positive and negative results accurately.

Conclusions About two-thirds of the commonly used FIT products performed acceptably on spiked samples of human hemoglobin. We called each testing program and determined the following seven programs conduct fecal occult blood testing: False negative fecal occult blood tests due to delayed sample return in colorectal cancer screening.

Fecal occult blood test products are either guaiac-based or immunochemical. A quantitative immunochemical fecal occult blood test for colorectal neoplasia.

See other articles in PMC that cite the published article. Colorectal cancer screening and surveillance: Non-laboratory healthcare professionals need access to reliable and valid testing results to make informed decisions when selecting a fecal occult blood test product. Limitations of this study included being unable to obtain information from three testing programs which assess FITs, thus limiting our generalizability, and proficiency testing programs not disclosing the amount of hemoglobin in their positive samples.


We were able to obtain results for FIT testing from four testing programs. Cascade colorectal cancer screening guidelines: Screening for colorectal neoplasms with new fecal occult blood tests: If an automated system is used, another issue to take into consideration is the cutoff point for hemoglobin detection.

Evaluation of Fecal Immunochemical Tests for CRC Screening

In turn, each participating laboratory receives a report of their performance, as well as a report summarizing the results of all participating laboratories. Please review our privacy hemossure. Estimation of the optimal cut off point in a new immunological faecal occult blood test in a corporate colorectal cancer screening programme.

Screening for familial colorectal cancer with a sensitive immunochemical fecal occult blood test: Cancer Epidemiol Biomarkers Prev. Some FIT products were evaluated by more than one program.

Agresti A, Coull BA. This is the first study we are aware of that has assessed proficiency testing results. The purpose of this study was to summarize the accuracy of results of individual FIT products across pathology proficiency testing programs.

Laboratories throughout the U. N Engl J Med. Colonoscopic evaluation of immunochemical fecal occult blood test for detection of colorectal neoplasia.